The role of Schwann cells in the development of human peripheral nerves: An electron microscopic study

H Cravioto - Journal of ultrastructure research, 1965 - Elsevier
The Schwann cells of the sciatic nerve and brachial plexuses of four human fetuses aged
12, 14, 16, and 22 weeks of intrauterine life, were studied with the electron microscope. Four
stages were recognized in the development of these cells:(a) pseudosyncytial,(b)
migration,(c) division of cells and separation of axons, and (d) myelination. During all stages
of development of human peripheral nerves, Schwann cells seem to have, as a
morphological and perhaps physiological function, the isolation of axons from the …