Nerve growth factor and the basal forebrain cholinergic system: a link in the etiopathology of neurodegenerative dementias?
EK Perry - Alzheimer Disease & Associated Disorders, 1990 - journals.lww.com
The discovery of a specific association between nerve growth factor (NGF) and basal
forebrain cholinergic neurons (BFCNs) marks the beginning of a new era of research into
neurodegenerative diseases such as Alzheimer disease (AD). Degeneration of BFCNs
appears to be one of the earliest and most prominent neuropathological features of a broad
range of diseases of the human brain that give rise to loss of memory and dementia
(including, in addition to Alzheimer disease, Parkinson disease, Lewy body dementia …
forebrain cholinergic neurons (BFCNs) marks the beginning of a new era of research into
neurodegenerative diseases such as Alzheimer disease (AD). Degeneration of BFCNs
appears to be one of the earliest and most prominent neuropathological features of a broad
range of diseases of the human brain that give rise to loss of memory and dementia
(including, in addition to Alzheimer disease, Parkinson disease, Lewy body dementia …