γ-secretase inhibitors: Notch so bad
GC Grosveld - Nature medicine, 2009 - nature.com
GC Grosveld
Nature medicine, 2009•nature.comγ-secretase inhibitors inhibit Notch, a transmembrane receptor that drives many cases of T
cell acute lymphoblastic leukemia—but there are safety concerns with such drugs.
Combining these inhibitors with glucocorticoids could provide a more effective and safer
approach (pages 50–58).
cell acute lymphoblastic leukemia—but there are safety concerns with such drugs.
Combining these inhibitors with glucocorticoids could provide a more effective and safer
approach (pages 50–58).
γ-secretase inhibitors inhibit Notch, a transmembrane receptor that drives many cases of T cell acute lymphoblastic leukemia—but there are safety concerns with such drugs. Combining these inhibitors with glucocorticoids could provide a more effective and safer approach (pages 50–58).
nature.com