Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia

MJ Minzenberg, AR Laird, S Thelen… - Archives of general …, 2009 - jamanetwork.com
Context Prefrontal cortical dysfunction is frequently reported in schizophrenia. It remains
unclear whether this represents the coincidence of several prefrontal region-and process-
specific impairments or a more unitary dysfunction in a superordinate cognitive control
network. Whether these impairments are properly considered reflective of hypofrontality vs
hyperfrontality remains unresolved. Objectives To test whether common nodes of the
cognitive control network exhibit altered activity across functional neuroimaging studies of …