Arterial spin labeling (ASL) perfusion fMRI data differ in important respects from the more
familiar blood oxygen level-dependent (BOLD) fMRI data and require specific processing
strategies. In this paper, we examined several factors that may influence ASL data analysis,
including data storage bit resolution, motion correction, preprocessing for cerebral blood
flow (CBF) calculations and nuisance covariate modeling. Continuous ASL data were
collected at 3 T from 10 subjects while they performed a simple sensorimotor task with an …