Homocystinuria: an enzymatic defect

SH Mudd, JD Finkelstein, F Irreverre, L Laster - Science, 1964 - science.org
SH Mudd, JD Finkelstein, F Irreverre, L Laster
Science, 1964science.org
|LAEWWE( L OMOCYSTM" Page 1 column was washed bypassing through 25 ml of O.4M
saline phosphate buffer (O.4M NaCl, O.05Msodium phosphate buffer, pH 6.7) and then
through 25 ml of 0.55M saline A. TESTIS "dX B. LIVER C. MUSCLE D. EGG REF. 1.683 1.705
1.746 Fig. Distribution of Cancer borealis DNA from various tissues in CsCl buoyant-density
gradient. DNA samples (2 to 3 ,ug) were centrifuged with 1 ,ug N"5Pseudomonas aeruginosa
DNA as a reference at 44,770 rev/min in 7.7 molal CsCl solution at 25'C for20 hours. Ultraviolet …
A deficiency, or absence, of cystathionine synthetase activity has been demonstrated in liver obtained from a mentally retarded child with homocystinuria.
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