Identification of a major latent nuclear antigen, LNA-1, in the human herpesvirus 8 genome.

P Kellam, C Boshoff, D Whitby, S Matthews… - Journal of human …, 1997 - europepmc.org
P Kellam, C Boshoff, D Whitby, S Matthews, RA Weiss, SJ Talbot
Journal of human virology, 1997europepmc.org
Objectives Human herpesvirus 8 (HHV-8) is strongly associated with all forms of Kaposi's
sarcoma (KS) and with primary effusion lymphomas (PEL). KS patients' sera are
immunoreactive against discrete nuclear localizing antigens in PEL cell lines. This study
sought to identify and characterize these nuclear localizing proteins.
Objectives
Human herpesvirus 8 (HHV-8) is strongly associated with all forms of Kaposi's sarcoma (KS) and with primary effusion lymphomas (PEL). KS patients' sera are immunoreactive against discrete nuclear localizing antigens in PEL cell lines. This study sought to identify and characterize these nuclear localizing proteins.
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