[HTML][HTML] The chromatin regulator BRPF3 preferentially activates the HBO1 acetyltransferase but is dispensable for mouse development and survival
To interpret epigenetic information, chromatin readers utilize various protein domains for
recognition of DNA and histone modifications. Some readers possess multidomains for
modification recognition and are thus multivalent. Bromodomain-and plant homeodomain-
linked finger-containing protein 3 (BRPF3) is such a chromatin reader, containing two plant
homeodomain-linked fingers, one bromodomain and a PWWP domain. However, its
molecular and biological functions remain to be investigated. Here, we report that …
recognition of DNA and histone modifications. Some readers possess multidomains for
modification recognition and are thus multivalent. Bromodomain-and plant homeodomain-
linked finger-containing protein 3 (BRPF3) is such a chromatin reader, containing two plant
homeodomain-linked fingers, one bromodomain and a PWWP domain. However, its
molecular and biological functions remain to be investigated. Here, we report that …