Macrophages are one of the most abundant leucocytes in the intestinal mucosa where they
are essential for maintaining homeostasis. However, they are also implicated in the
pathogenesis of disorders such as inflammatory bowel disease (IBD), offering potential
targets for novel therapies. Here we discuss the function of intestinal monocytes and
macrophages during homeostasis and describe how these populations and their functions
change during infection and inflammation. Furthermore, we review the current evidence that …