Treatment trends and outcomes of small-cell carcinoma of the bladder: in regard to Koay et al.(Int J Radiat Oncol Biol Phys 2011 Oct 20)
N Ismaili - International journal of radiation oncology, biology …, 2012 - redjournal.org
The cause-specific and overall 5-year survival was significantly higher in the triweekly arm
compared with the weekly arm (88.7% vs. 66.5%, respectively; hazard ratio, 0.375; 95%
confidence interval, 0.154–0.914; p= 0.03; Fig.). Also the Grade 3–4 neutropenia was higher
in the weekly arm than in the triweekly arm (39.2% and 22.6%, respectively, p= 0.03). This
study postulates that higher peak concentration of cisplatin may be more critical in
enhancing the synergy of chemoradiation than the weekly cisplatin exposure. Also, the high …
compared with the weekly arm (88.7% vs. 66.5%, respectively; hazard ratio, 0.375; 95%
confidence interval, 0.154–0.914; p= 0.03; Fig.). Also the Grade 3–4 neutropenia was higher
in the weekly arm than in the triweekly arm (39.2% and 22.6%, respectively, p= 0.03). This
study postulates that higher peak concentration of cisplatin may be more critical in
enhancing the synergy of chemoradiation than the weekly cisplatin exposure. Also, the high …