Sex differences in coronary heart disease: why are women so superior? The 1995 Ancel Keys Lecture

E Barrett-Connor - Circulation, 1997 - Am Heart Assoc
E Barrett-Connor
Circulation, 1997Am Heart Assoc
It was a great privilege to be asked to give the 1995 Ancel Keys lecture, following five very
distinguished colleagues [Geoffrey Rose, Henry Blackburn, Jeremiah Stamler, Fred Epstein,
and William Kannel] and honoring Ancel Keys. It is difficult to imagine how little we would
know about CHD without their contributions.The subject of my lecture,“Why are women so
superior with regard to coronary heart disease?,” is surely one of the most interesting of all
epidemiological questions. My intention is to illustrate methodological problems and review …
It was a great privilege to be asked to give the 1995 Ancel Keys lecture, following five very distinguished colleagues [Geoffrey Rose, Henry Blackburn, Jeremiah Stamler, Fred Epstein, and William Kannel] and honoring Ancel Keys. It is difficult to imagine how little we would know about CHD without their contributions.
The subject of my lecture,“Why are women so superior with regard to coronary heart disease?,” is surely one of the most interesting of all epidemiological questions. My intention is to illustrate methodological problems and review old and new provocative results, making inferences from a variety of disciplines. My focus is on the origin of the gender gap, not postmenopausal estrogen therapy. There will be no conclusions, only reconstruction. My lecture is outlined in Fig 1.
Am Heart Assoc