The association of Tyro3/Axl/Mer signaling with inflammatory response, disease activity in patients with primary Sjögren's syndrome
B Qin, J Wang, N Ma, M Yang, H Fu, Y Liang, F Huang… - Joint Bone Spine, 2015 - Elsevier
Abstract Objectives Defects in Tyro3/Axl/Mer signaling may lead to impaired phagocytosis of
apoptotic cells, eventually contributing to the development of autoimmune disease. The
association of TAM signaling with several autoimmune disease has been investigated, but it
remains unclear in primary Sjögren's syndrome. Therefore, the aim of this study was to
evaluate the level of TAM signaling in primary Sjögren's syndrome with its clinical
significance. Methods Real-Time Polymerase Chain Reaction was used to determine the …
apoptotic cells, eventually contributing to the development of autoimmune disease. The
association of TAM signaling with several autoimmune disease has been investigated, but it
remains unclear in primary Sjögren's syndrome. Therefore, the aim of this study was to
evaluate the level of TAM signaling in primary Sjögren's syndrome with its clinical
significance. Methods Real-Time Polymerase Chain Reaction was used to determine the …