Do prostaglandins stimulate LH release and thereby cause luteolysis?
AP Labhsetwar - 1973 - cabidigitallibrary.org
AP Labhsetwar
1973•cabidigitallibrary.orgIt is contended that the findings of Cerini and Christie [Prostaglandins 2, 433], that the
luteolytic effect of PGF2 alpha is mediated through increased secretion of LH, is not proven
since (a) the dose used was 5 mu g/h and other workers had already shown that luteolysis
does not occur even at 25 mu g/h, and (b) no one has demonstrated that LH does have a
luteolytic action in sheep.
luteolytic effect of PGF2 alpha is mediated through increased secretion of LH, is not proven
since (a) the dose used was 5 mu g/h and other workers had already shown that luteolysis
does not occur even at 25 mu g/h, and (b) no one has demonstrated that LH does have a
luteolytic action in sheep.
Abstract
It is contended that the findings of Cerini and Christie [Prostaglandins 2, 433], that the luteolytic effect of PGF2 alpha is mediated through increased secretion of LH, is not proven since (a) the dose used was 5 mu g/h and other workers had already shown that luteolysis does not occur even at 25 mu g/h, and (b) no one has demonstrated that LH does have a luteolytic action in sheep.
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