Monocyte chemoattractant protein-1 (MCP-1) in inflammatory joint diseases and its involvement in the cytokine network of rheumatoid synovium
M Harigai, M Hara, T Yoshimura, EJ Leonard… - Clinical immunology and …, 1993 - Elsevier
Macrophages infiltrated into synovium play an important role in joint destruction in
inflammatory joint diseases. In this study we focused on the production of monocyte
chemoattractant protein-1 (MCP-1), a recently identified monocyte chemotactic protein, by
inflammatory synovium. Synovial fluid (SF) from rheumatoid arthritis (RA), osteoarthritis,
gout, and traumatic arthritis contained MCP-1. MCP-1 was produced in the synovium of
patients with RA and other inflammatory joint disease in in vitro culture systems; differences …
inflammatory joint diseases. In this study we focused on the production of monocyte
chemoattractant protein-1 (MCP-1), a recently identified monocyte chemotactic protein, by
inflammatory synovium. Synovial fluid (SF) from rheumatoid arthritis (RA), osteoarthritis,
gout, and traumatic arthritis contained MCP-1. MCP-1 was produced in the synovium of
patients with RA and other inflammatory joint disease in in vitro culture systems; differences …