[HTML][HTML] Analysis of Intimal Proteoglycans in Atherosclerosis-prone and Atherosclerosis-resistant Human Arteries by Mass Spectrometry* S

P Talusan, S Bedri, S Yang, T Kattapuram… - Molecular & Cellular …, 2005 - ASBMB
The propensity to develop atherosclerosis varies markedly among different sites in the
human vasculature. To determine a possible cause for such differences in atherosclerosis
susceptibility, a proteomics-based approach was used to assess the extracellular
proteoglycan core protein composition of intimal hyperplasia from both the atherosclerosis-
prone internal carotid artery and the atherosclerosis-resistant internal thoracic artery. The
intimal proteoglycan composition in these preatherosclerotic lesions was found to be more …