[HTML][HTML] The organization, promoter analysis, and expression of the human PPARγ gene
L Fajas, D Auboeuf, E Raspé, K Schoonjans… - Journal of Biological …, 1997 - ASBMB
PPARγ is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of
the human PPARγ cDNA and gene was determined, and its promoters and tissue-specific
expression were functionally characterized. Similar to the mouse, two PPAR isoforms,
PPARγ1 and PPARγ2, were detected in man. The relative expression of human PPARγ was
studied by a newly developed and sensitive reverse transcriptase-competitive polymerase
chain reaction method, which allowed us to distinguish between PPARγ1 and γ2 mRNA. In …
the human PPARγ cDNA and gene was determined, and its promoters and tissue-specific
expression were functionally characterized. Similar to the mouse, two PPAR isoforms,
PPARγ1 and PPARγ2, were detected in man. The relative expression of human PPARγ was
studied by a newly developed and sensitive reverse transcriptase-competitive polymerase
chain reaction method, which allowed us to distinguish between PPARγ1 and γ2 mRNA. In …