Myelodysplastic syndrome with monosomy 7 in a patient with XY gonadal dysgenesis (incomplete testicular feminization)

YV Olshanskaya, AI Udovichenko… - Cancer genetics …, 2009 - cancergeneticsjournal.org
An array of congenital disorders carries a high risk of myeloid leukemia, including Fanconi
anemia, severe congenital neutropenia, ShwachmaneDiamond syndrome,
neurofibromatosis type 1, cerebellar ataxia, and possibly Down syndrome [1]. In contrast to
other congenital disorders, the incidence of leukemia does not seem to be increased in
patients with some of the most frequent constitutional conditions, such as Turner and
Klinefelter syndromes [2e4]. Hematological malignancies in patients with other sex …