The platelet hyporeactivity of extremely low birth weight neonates is age-dependent

FJ Bednarek, S Bean, MR Barnard, AL Frelinger… - Thrombosis research, 2009 - Elsevier
INTRODUCTION: We have previously demonstrated that, as compared to adults, the
platelets of extremely low birth weight (ELBW) neonates are markedly hyporeactive on day 0–
1 of life. The purpose of this study was to examine the age dependency of this hyporeactivity.
MATERIALS AND METHODS: On days 0–1, 3–4, and 10–14, peripheral blood was collected
from 14 stable ELBW neonates and compared to peripheral blood from normal adults run in
parallel. Whole blood flow cytometry was used to examine the activation-dependent …