[HTML][HTML] Novel variants in the SOHLH2 gene are implicated in human premature ovarian failure

Y Qin, X Jiao, R Dalgleish, S Vujovic, J Li, JL Simpson… - Fertility and …, 2014 - Elsevier
Objective To determine whether variants in the SOHLH2 gene contribute to human
premature ovarian failure (POF) in different ethnicities. Design Case-control genetic study.
Setting University hospitals. Patient (s) Chinese (364 cases) and Serbian (197 cases)
women with nonsyndromic POF and ethnically matched controls. Intervention (s) None. Main
Outcome Measure (s) Variation analysis of the SOHLH2 gene. Result (s) Eleven novel
heterozygous variants were identified in cohorts of POF but were absent in matched …