Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in Iran
Background The study documented the emergence of new forms of resistant bacilli (totally
drug-resistant [TDR] or super extensively drug-resistant [XDR] tuberculosis [TB] strains)
among patients with multidrug-resistant TB (MDR-TB). Methods Susceptibility testing against
first-and second-line drugs was performed on isolated Mycobacterium tuberculosis strains.
Subsequently, the strains identified as XDR or TDR M tuberculosis were subjected to
spoligotyping and variable numbers of tandem repeats (VNTR). Results Of 146 MDR-TB …
drug-resistant [TDR] or super extensively drug-resistant [XDR] tuberculosis [TB] strains)
among patients with multidrug-resistant TB (MDR-TB). Methods Susceptibility testing against
first-and second-line drugs was performed on isolated Mycobacterium tuberculosis strains.
Subsequently, the strains identified as XDR or TDR M tuberculosis were subjected to
spoligotyping and variable numbers of tandem repeats (VNTR). Results Of 146 MDR-TB …
