[HTML][HTML] Is there a role for the ACE2 receptor in SARS‐CoV‐2 interactions with platelets?

RA Campbell, E Boilard, MT Rondina - Journal of Thrombosis and …, 2021 - Elsevier
There is an urgent need to understand the underlying mechanisms contributing to
thrombotic and inflammatory complications during COVID‐19. Data from independent
groups have identified that platelets are hyperreactive during COVID‐19. Platelet
hyperreactivity is accompanied by changes in platelet gene expression, and enhanced
interactions between platelets and leukocytes. In some patients, SARS‐CoV‐2 mRNA has
been detected in platelets. Together, this suggests that SARS‐CoV‐2 may interact with …