Cholesterol transport between cells and high-density lipoproteins

WJ Johnson, FH Mahlberg, GH Rothblat… - Biochimica et Biophysica …, 1991 - Elsevier
The subject of this review, cholester,. t transpo~'t between cells and high-density lipoproteins
(HDL), is believed to bc of physiological relevance because it is central to'reverse
cholesterol transport'in vivo. As discussed in detail below, reverse cholesterol transport is
the process whereby cholesterol is transported from peripheral (non-hepatic) cells to the
liver for catabolism and removal from the body. Efflux of cholesterol from pcriphcral cells to
HDL is the first step in reverse cholcsterol transport and it is critical for cholesterol …