[CITATION][C] Primary pulmonary hypertension in a patient with a familial platelet storage pool disease: role of serotonin
P Herve, L Drouet, C Dosquet, JM Launay… - The American journal of …, 1990 - Elsevier
P rimary pulmonary hypertension is a disease of un-known origin. Among various etiologic
clues, the possibility has been raised that abnormalities in platelet endothelial interactions
might be involved in the pathogenesis of primary pulmonary hypertension [1, 2]. Platelets
could be involved through the release of vasoactive substances or of substances that
stimulate cellular proliferation [l]. However, the role of platelets in the genesis of pulmonary
hypertension has not yet been demonstrated. Abnormalities of platelet function have been …
clues, the possibility has been raised that abnormalities in platelet endothelial interactions
might be involved in the pathogenesis of primary pulmonary hypertension [1, 2]. Platelets
could be involved through the release of vasoactive substances or of substances that
stimulate cellular proliferation [l]. However, the role of platelets in the genesis of pulmonary
hypertension has not yet been demonstrated. Abnormalities of platelet function have been …