regulatory T cells
S Read, KJ MALOY, F POWRIE - The Autoimmune Diseases, 2006 - Elsevier
Publisher Summary This chapter describes a number of regulatory T cell types—namely,
CD4+ CD25+, Tr1, Th3, NKT, and CD8+ with particular emphasis on CD4+ CD25+ Treg
cells. It is noted that with the identification of the Foxp3 transcription factor that cements the
link between Treg function and self-tolerance, interest in Tregs has reached tremendously.
Furthermore, there is a growing realization of the crucial physiologic role that Tregs play in
maintaining the delicate equilibrium between immune responsiveness and immune …
CD4+ CD25+, Tr1, Th3, NKT, and CD8+ with particular emphasis on CD4+ CD25+ Treg
cells. It is noted that with the identification of the Foxp3 transcription factor that cements the
link between Treg function and self-tolerance, interest in Tregs has reached tremendously.
Furthermore, there is a growing realization of the crucial physiologic role that Tregs play in
maintaining the delicate equilibrium between immune responsiveness and immune …