[HTML][HTML] Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin αvβ3
ML Kireeva, SCT Lam, LF Lau - Journal of Biological Chemistry, 1998 - ASBMB
Cyr61 is a member of a family of growth factor-inducible immediate-early gene products
thought to act cooperatively with the activities of growth factors. Upon synthesis, Cyr61 is
secreted and is predominantly incorporated into the extracellular matrix. Recently, we
demonstrated that Cyr61 promotes cell adhesion and migration and augments growth factor-
induced DNA synthesis (Kireeva, ML, Mo, F.-E., Yang, GP, and Lau, LF (1996) Mol. Cell.
Biol. 16, 1326–1334). In the present study, we investigated possible candidate receptor (s) …
thought to act cooperatively with the activities of growth factors. Upon synthesis, Cyr61 is
secreted and is predominantly incorporated into the extracellular matrix. Recently, we
demonstrated that Cyr61 promotes cell adhesion and migration and augments growth factor-
induced DNA synthesis (Kireeva, ML, Mo, F.-E., Yang, GP, and Lau, LF (1996) Mol. Cell.
Biol. 16, 1326–1334). In the present study, we investigated possible candidate receptor (s) …