[PDF][PDF] T-cell development: a role for self-peptides in positive selection

CA Janeway - Current biology, 1999 - cell.com
CA Janeway
Current biology, 1999cell.com
T-cell development: A role for self-peptides in positive selection Page 1 R342 Dispatch T-cell
development: A role for self-peptides in positive selection Charles A. Janeway Jr. An important
issue for immunologists is the difference between the two main processes that determine the
mature repertoire of T-cell receptors, termed positive and negative selection. Recent papers
have addressed the role of self-peptides in the process of positive selection. Address: Section
of Immunobiology, Yale University School of Medicine and The Howard Hughes Medical …
Abstract
An important issue for immunologists is the difference between the two main processes that determine the mature repertoire of T-cell receptors, termed positive and negative selection. Recent papers have addressed the role of self-peptides in the process of positive selection.
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