Differential neurogenesis and gliogenesis by local and migrating neural stem cells in the olfactory bulb

N Fukushima, K Yokouchi, K Kawagishi… - Neuroscience …, 2002 - Elsevier
The rostral migratory stream (RMS) is a unique forebrain structure that provides a long-
distance migratory route for the neural stem cells of the periventricular region towards the
olfactory bulb (OB). The purpose of the study presented here is to examine the extent of
neurogenesis and gliogenesis by the neural stem cells of different origins (periventricular vs.
intrabulbar) in the OB. After the RMS had been subjected to injury, the rats received
intraperitoneal injections of 5-bromodeoxyuridine (BrdU) and were further reared for 2 …