Platelet aggregation and neutrophil sequestration in the mesenteric circulation in inflammatory bowel disease
CE Collins, DS Rampton, J Rogers… - European journal of …, 1997 - journals.lww.com
Results: In UC and CD, but not in controls, fewer neutrophils were found in blood draining
the intestine compared with that supplying it (arteriovenous gradient median 1.0× 10 9/l
(interquartile range 0.2-1.3) for UC, P< 0.05; 0.8 (0.2-1.5) for CD, P< 0.02; 0.4 (-0.3-1.1) for
controls, P= NS). In CD, increased numbers of circulating platelet aggregates were identified
in venous samples (platelet aggregate ratio 0.83 (0.71-0.93)) than in paired arterial samples
(0.99 (0.95-1.01), P< 0.02) and control venous samples (0.99 (0.93-0.97), P< 0.05).
the intestine compared with that supplying it (arteriovenous gradient median 1.0× 10 9/l
(interquartile range 0.2-1.3) for UC, P< 0.05; 0.8 (0.2-1.5) for CD, P< 0.02; 0.4 (-0.3-1.1) for
controls, P= NS). In CD, increased numbers of circulating platelet aggregates were identified
in venous samples (platelet aggregate ratio 0.83 (0.71-0.93)) than in paired arterial samples
(0.99 (0.95-1.01), P< 0.02) and control venous samples (0.99 (0.93-0.97), P< 0.05).
