Publisher Summary This chapter discusses the detection and quantification of
phosphotyrosine in proteins. Protein kinases can be differentiated according to their amino
acid specificity. Casein kinases of type II and the cAMP-dependent kinases phosphorylate
serine, while casein kinases of type I phosphorylate threonine and, to a lesser extent, serine.
Another group of kinases with strict specificity for tyrosine is described in the chapter. Most
tyrosine-specific protein kinase activities detected to date are implicated in cell growth …