Role of regulatory T cells in allergy and asthma
O Akbari, P Stock, RH DeKruyff, DT Umetsu - Current opinion in …, 2003 - Elsevier
O Akbari, P Stock, RH DeKruyff, DT Umetsu
Current opinion in immunology, 2003•ElsevierTh2 cells play a critical role in the pathogenesis of allergy and asthma. However, the
immunological mechanisms that downmodulate and protect against the development of
these disorders are poorly understood. A spectrum of CD4+ T cells, including Th3 cells, TR
cells, CD4+ CD25+ cells and NKT cells play a critical role in regulating these diseases. A
better understanding of the role of regulatory cells in allergic diseases may lead to the
identification of novel therapeutic targets.
immunological mechanisms that downmodulate and protect against the development of
these disorders are poorly understood. A spectrum of CD4+ T cells, including Th3 cells, TR
cells, CD4+ CD25+ cells and NKT cells play a critical role in regulating these diseases. A
better understanding of the role of regulatory cells in allergic diseases may lead to the
identification of novel therapeutic targets.
Th2 cells play a critical role in the pathogenesis of allergy and asthma. However, the immunological mechanisms that downmodulate and protect against the development of these disorders are poorly understood. A spectrum of CD4+ T cells, including Th3 cells, TR cells, CD4+CD25+ cells and NKT cells play a critical role in regulating these diseases. A better understanding of the role of regulatory cells in allergic diseases may lead to the identification of novel therapeutic targets.
Elsevier