To the Editor: Dr Mukamal and colleagues1 reported that moderate alcohol consumption
reduces the risk of mortality following acute myocardial infarction. This conclusion, however,
is not warranted by their data. While unadjusted mortality was significantly less among
drinkers than abstainers, this difference became statistically nonsignificant after adjustment.
All the adjusted hazard ratios, regardless of the volume of alcohol consumed or the type of
adjustment, had 95% confidence intervals (CIs) that included 1.0. Unadjusted comparisons …