Human aminopeptidases: a review of the literature
GJ Sanderink, Y Artur, G Siest - 1988 - degruyter.com
GJ Sanderink, Y Artur, G Siest
1988•degruyter.comThe aminopeptidases constitute a group of enzymes with closely related activities. In clinical
chemistry the analysis of the aminopeptidases and of their multiple forms in serum has for a
long time been hindered by considerable confusion concerning their identification, and by a
lack of characterization. This is in part due to the often large, and sometimes overlapping
substrate specificities of the aminopeptidases. This paper reviews the biochemical
properties of the different aminopeptidases, the specificities of the assays used for their …
chemistry the analysis of the aminopeptidases and of their multiple forms in serum has for a
long time been hindered by considerable confusion concerning their identification, and by a
lack of characterization. This is in part due to the often large, and sometimes overlapping
substrate specificities of the aminopeptidases. This paper reviews the biochemical
properties of the different aminopeptidases, the specificities of the assays used for their …
Summary
The aminopeptidases constitute a group of enzymes with closely related activities. In clinical chemistry the analysis of the aminopeptidases and of their multiple forms in serum has for a long time been hindered by considerable confusion concerning their identification, and by a lack of characterization. This is in part due to the often large, and sometimes overlapping substrate specificities of the aminopeptidases.
This paper reviews the biochemical properties of the different aminopeptidases, the specificities of the assays used for their analysis in serum, some aspects of their multiple forms—which are especially known to occur for alanine äminopeptidase (EC 3.4. 11.2)—and the importance of the determination of aminopeptidases and their multiple forms in clinical chemistry.
De Gruyter