Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases
M Cesari, GP Rossi, AC Pessina - Journal of hypertension, 2002 - journals.lww.com
M Cesari, GP Rossi, AC Pessina
Journal of hypertension, 2002•journals.lww.comSeveral peptides of the RAS other than angiotensin (1–8) have been identified. They are
generally referred as 'angiotensin fragments': Ang (2–8), Ang (3–8) and Ang (1–7) and have
been detected in human tissues. There is evidence that they may play a functional role in
humans by acting in concert with angiotensin (1-8) and aldosterone. Available knowledge
on the pathways leading to synthesis and degradation of angiotensin fragments, as well as
on their interactions with receptors and on their possible role in cardiovascular homeostasis …
generally referred as 'angiotensin fragments': Ang (2–8), Ang (3–8) and Ang (1–7) and have
been detected in human tissues. There is evidence that they may play a functional role in
humans by acting in concert with angiotensin (1-8) and aldosterone. Available knowledge
on the pathways leading to synthesis and degradation of angiotensin fragments, as well as
on their interactions with receptors and on their possible role in cardiovascular homeostasis …
Abstract
Several peptides of the RAS other than angiotensin (1–8) have been identified. They are generally referred as ‘angiotensin fragments': Ang (2–8), Ang (3–8) and Ang (1–7) and have been detected in human tissues. There is evidence that they may play a functional role in humans by acting in concert with angiotensin (1-8) and aldosterone. Available knowledge on the pathways leading to synthesis and degradation of angiotensin fragments, as well as on their interactions with receptors and on their possible role in cardiovascular homeostasis and disease are reviewed.
Lippincott Williams & Wilkins