T cell dynamics in HIV-1 infection
DR Clark, RJ de Boer, KC Wolthers, F Miedema - Advances in immunology, 1999 - Elsevier
Publisher Summary This chapter discusses the T cell dynamics in HIV-1 infection. One of the
most prominent features of HIV-1 infection is CD4+ T cell depletion. This statement is widely
used in papers on HIV-1 research; however, the truth is that it fails to describe the complex
change in the representation of T cell subsets during HIV-1 infection. HIV-1 infection is a
dynamic process with much more virus “turn over” than was previously anticipated. This view
of rapid CD4+ T cell turnover is challenged by studies on T cell telomere length, showing no …
most prominent features of HIV-1 infection is CD4+ T cell depletion. This statement is widely
used in papers on HIV-1 research; however, the truth is that it fails to describe the complex
change in the representation of T cell subsets during HIV-1 infection. HIV-1 infection is a
dynamic process with much more virus “turn over” than was previously anticipated. This view
of rapid CD4+ T cell turnover is challenged by studies on T cell telomere length, showing no …
