Since its' discovery over 20 years ago, BDNF has been shown to play a key role in neuronal
survival, in promoting neuronal regeneration following injury, regulating transmitter systems
and attenuating neural-immune responses. Estrogen's actions in the young and mature
brain, and its role in neurodegenerative diseases in many cases overlaps with those
observed for BDNF. Reduced estrogen and BDNF are observed in patients with Parkinson's
disease and Alzheimer's disease, while high estrogen levels are a risk factor for …