[HTML][HTML] Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth muscle cell migration
DK Swertfeger, G Bu, DY Hui - Journal of Biological Chemistry, 2002 - ASBMB
This research was undertaken to identify the cell surface receptor responsible for mediating
apolipoprotein E (apoE) inhibition of platelet-derived growth factor (PDGF)-directed smooth
muscle cell migration. Initial studies revealed the expression of the low density lipoprotein
receptor (LDLR), the LDL receptor-related protein (LRP), the very low density lipoprotein
receptor (VLDL), and apoE receptor-2 in mouse aortic smooth muscle cells. Smooth muscle
cells isolated from LDLR-null, VLDL-null, and apoE receptor-2-null mice were responsive to …
apolipoprotein E (apoE) inhibition of platelet-derived growth factor (PDGF)-directed smooth
muscle cell migration. Initial studies revealed the expression of the low density lipoprotein
receptor (LDLR), the LDL receptor-related protein (LRP), the very low density lipoprotein
receptor (VLDL), and apoE receptor-2 in mouse aortic smooth muscle cells. Smooth muscle
cells isolated from LDLR-null, VLDL-null, and apoE receptor-2-null mice were responsive to …