Autoimmune thrombocytopenic purpura and Helicobacter pylori infection

M Michel, M Khellaf, L Desforges, K Lee… - Archives of internal …, 2002 - jamanetwork.com
Background The mechanisms triggering the production of platelet autoantibodies in
autoimmune thrombocytopenic purpura (AITP) are poorly understood. Recently, marked
improvements in platelet counts have been reported in patients with AITP and
concurrentHelicobacter pyloriinfection after eradication ofH pyloriby a standard antibiotic
regimen. We looked for an association betweenH pyloriinfection and AITP in adults.
Methods Fifty-one adults of white French origin, negative for human immunodeficiency virus …