No requirement of α-internexin for nervous system development and for radial growth of axons
F Levavasseur, Q Zhu, JP Julien - Molecular brain research, 1999 - Elsevier
α-Internexin is a type IV intermediate filament protein that is expressed abundantly in
neurons during development of the peripheral and central nervous systems as well as in few
neurons of the adult central nervous system. It has been suggested that α-internexin may act
as a scaffold for the formation of neuronal intermediate filaments during early development.
In addition, recent reports suggest that α-internexin could play a major role in two
degenerative neurological disorders. We report here an analysis of mice with a targeted …
neurons during development of the peripheral and central nervous systems as well as in few
neurons of the adult central nervous system. It has been suggested that α-internexin may act
as a scaffold for the formation of neuronal intermediate filaments during early development.
In addition, recent reports suggest that α-internexin could play a major role in two
degenerative neurological disorders. We report here an analysis of mice with a targeted …
