Association of apolipoprotein E polymorphisms with normal tension glaucoma in a Chinese population
CY Lam, BJ Fan, DY Wang, POS Tam… - Journal of …, 2006 - journals.lww.com
Purpose To evaluate the role of apolipoprotein E (APOE) polymorphisms in primary open
angle glaucoma (POAG). Methods A cohort of 400 unrelated Chinese POAG patients was
examined, including 294 cases of high tension glaucoma (HTG) and 106 with normal
tension glaucoma (NTG). Also studied were 300 unrelated Chinese control subjects. The
genotypes of the APOE polymorphisms in exon 4 and in the promoter at positions− 491,−
427, and− 219 were determined by polymerase chain reaction and restriction endonuclease …
angle glaucoma (POAG). Methods A cohort of 400 unrelated Chinese POAG patients was
examined, including 294 cases of high tension glaucoma (HTG) and 106 with normal
tension glaucoma (NTG). Also studied were 300 unrelated Chinese control subjects. The
genotypes of the APOE polymorphisms in exon 4 and in the promoter at positions− 491,−
427, and− 219 were determined by polymerase chain reaction and restriction endonuclease …