Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States
MA Hauser, DF Sena, J Flor, J Walter… - Journal of …, 2006 - journals.lww.com
Purpose Previous studies have suggested that Optineurin (OPTN) sequence variants
contribute to low-tension glaucoma (LTG) in ethnically homogeneous populations. The
purpose of this study is to evaluate the prevalence of OPTN sequence variants in an
ethnically diverse population of LTG patients from the United States, and to describe the
phenotype of patients with OPTN sequence variants preferentially found in LTG patients.
Methods Genomic DNA purified from 67 LTG patients was screened for DNA sequence …
contribute to low-tension glaucoma (LTG) in ethnically homogeneous populations. The
purpose of this study is to evaluate the prevalence of OPTN sequence variants in an
ethnically diverse population of LTG patients from the United States, and to describe the
phenotype of patients with OPTN sequence variants preferentially found in LTG patients.
Methods Genomic DNA purified from 67 LTG patients was screened for DNA sequence …