A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
DT Wong, JS Horng, FP Bymaster, KL Hauser… - Life sciences, 1974 - Elsevier
DT Wong, JS Horng, FP Bymaster, KL Hauser, BB Molloy
Life sciences, 1974•ElsevierLilly 110140 is a highly selective inhibitor of serotonin uptake into synaptosomes of rat brain,
unlike previous monoamine uptake inhibitors that also inhibit the uptake of norepinephrine
and dopamine. Lilly 110140 should be useful in studying the function of serotoninergic
neurons and may be helpful in clariying the role of serotonin in certain types of mental
depression.
unlike previous monoamine uptake inhibitors that also inhibit the uptake of norepinephrine
and dopamine. Lilly 110140 should be useful in studying the function of serotoninergic
neurons and may be helpful in clariying the role of serotonin in certain types of mental
depression.
Abstract
Lilly 110140 is a highly selective inhibitor of serotonin uptake into synaptosomes of rat brain, unlike previous monoamine uptake inhibitors that also inhibit the uptake of norepinephrine and dopamine. Lilly 110140 should be useful in studying the function of serotoninergic neurons and may be helpful in clariying the role of serotonin in certain types of mental depression.
Elsevier
