Persistent elevation of cell-free fetal DNA levels in maternal plasma after selective laser coagulation of chorionic plate anastomoses in severe midgestational twin-twin …
T Wataganara, E Gratacos, J Jani, J Becker… - American journal of …, 2005 - Elsevier
OBJECTIVE: This study was undertaken to determine whether laser thermocoagulation for
twin-twin transfusion syndrome (TTTS) causes increased cell-free fetal DNA levels in
maternal plasma, potentially as a result of placental injury. STUDY DESIGN: We enrolled 34
patients with twin pregnancies complicated by severe TTTS who underwent fetoscopic
selective laser ablation of placental vascular anastomoses. Blood samples were drawn
before and sequentially after the procedure. Fetal DNA in maternal plasma was quantified …
twin-twin transfusion syndrome (TTTS) causes increased cell-free fetal DNA levels in
maternal plasma, potentially as a result of placental injury. STUDY DESIGN: We enrolled 34
patients with twin pregnancies complicated by severe TTTS who underwent fetoscopic
selective laser ablation of placental vascular anastomoses. Blood samples were drawn
before and sequentially after the procedure. Fetal DNA in maternal plasma was quantified …