Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor
SC Satchell, SJ Harper, JE Tooke… - Journal of the …, 2002 - journals.lww.com
Vascular endothelial growth factor (VEGF) is abundantly expressed by podocytes, but its
role in glomeruli is unknown. Angiopoietins are endothelial cell growth factors that function
in concert with VEGF but have not previously been observed in human glomeruli.
Angiopoietin 1 (Ang1) acts via the endothelial receptor Tie2 to promote maturation and
stabilization of blood vessels, resisting angiogenesis and opposing some actions of VEGF.
Ang1, Ang2, Tie2, and VEGF expression in normal human renal cortex was examined with …
role in glomeruli is unknown. Angiopoietins are endothelial cell growth factors that function
in concert with VEGF but have not previously been observed in human glomeruli.
Angiopoietin 1 (Ang1) acts via the endothelial receptor Tie2 to promote maturation and
stabilization of blood vessels, resisting angiogenesis and opposing some actions of VEGF.
Ang1, Ang2, Tie2, and VEGF expression in normal human renal cortex was examined with …
