Androgen receptor and hepatocarcinogenesis: what do we learn from HCC mouse models?
L Zender, S Kubicka - Gastroenterology, 2008 - gastrojournal.org
Hepatocellular carcinoma (HCC) represents a major health problem worldwide with steadily
increasing incidence rates, particularly in developed Western countries. Currently, HCC is
ranking the 5th most common malignancy in men and the 8th most common tumor in
women. 1, 2 Initially, it was thought that higher HCC incidence rates in men could be
ascribed to a predominance of certain etiologies in male hepatocarcinogenesis; it was also
speculated that different smoking and drinking habits could play into the observed gender …
increasing incidence rates, particularly in developed Western countries. Currently, HCC is
ranking the 5th most common malignancy in men and the 8th most common tumor in
women. 1, 2 Initially, it was thought that higher HCC incidence rates in men could be
ascribed to a predominance of certain etiologies in male hepatocarcinogenesis; it was also
speculated that different smoking and drinking habits could play into the observed gender …