A fatal granulomatous disease of childhood: the clinical, pathological, and laboratory features of a new syndrome
RA BRIDGES, H BERENDES… - AMA journal of diseases …, 1959 - jamanetwork.com
In 1950, a 12-month-old child was referred to the University of Minnesota Hospitals with a
syndrome consisting of chronic suppurative lymphadenitis, hepatosplenomegaly, pulmonary
infiltrations, and an eczematoid dermatitis about the eyes, nose, and mouth. Since then we
have seen three other children with an almost identical clinical picture. This syndrome
appears to be a distinct clinical entity not previously described in the medical literature. This
syndrome follows a malignant course and at this time has been responsible for the death of …
syndrome consisting of chronic suppurative lymphadenitis, hepatosplenomegaly, pulmonary
infiltrations, and an eczematoid dermatitis about the eyes, nose, and mouth. Since then we
have seen three other children with an almost identical clinical picture. This syndrome
appears to be a distinct clinical entity not previously described in the medical literature. This
syndrome follows a malignant course and at this time has been responsible for the death of …