Regulation of ion transport by the NHERF family of PDZ proteins
S Shenolikar, JW Voltz, R Cunningham… - …, 2004 - journals.physiology.org
S Shenolikar, JW Voltz, R Cunningham, EJ Weinman
Physiology, 2004•journals.physiology.orgNHERFs are the best-studied apical PDZ proteins that are highly expressed in epithelial
cells. Molecular and cellular studies over the past decade show that NHERFs regulate the
targeting or trafficking of ion transporters and other membrane proteins and transduce
physiological and pathophysiological signals that regulate ion homeostasis in mammals.
cells. Molecular and cellular studies over the past decade show that NHERFs regulate the
targeting or trafficking of ion transporters and other membrane proteins and transduce
physiological and pathophysiological signals that regulate ion homeostasis in mammals.
NHERFs are the best-studied apical PDZ proteins that are highly expressed in epithelial cells. Molecular and cellular studies over the past decade show that NHERFs regulate the targeting or trafficking of ion transporters and other membrane proteins and transduce physiological and pathophysiological signals that regulate ion homeostasis in mammals.
American Physiological Society