[PDF][PDF] Signaling takes a breath–new quantitative perspectives on bioenergetics and signal transduction
Immune cells are in constant need of energy for both basic housekeeping and specific
immune functions. Increased energy demand during lymphocyte stimulation is coordinated
by signal transduction pathways. This review explores the interface between lymphocyte
signaling and energy metabolism. In particular, it discusses recent work that allows weighing
signaling routes with respect to their role in the regulation of energy metabolism during
lymphocyte activation.
immune functions. Increased energy demand during lymphocyte stimulation is coordinated
by signal transduction pathways. This review explores the interface between lymphocyte
signaling and energy metabolism. In particular, it discusses recent work that allows weighing
signaling routes with respect to their role in the regulation of energy metabolism during
lymphocyte activation.
Abstract
Immune cells are in constant need of energy for both basic housekeeping and specific immune functions. Increased energy demand during lymphocyte stimulation is coordinated by signal transduction pathways. This review explores the interface between lymphocyte signaling and energy metabolism. In particular, it discusses recent work that allows weighing signaling routes with respect to their role in the regulation of energy metabolism during lymphocyte activation.
cell.com
