Is hypothyroidism a risk factor for non-alcoholic steatohepatitis?

S Liangpunsakul, N Chalasani - Journal of clinical …, 2003 - journals.lww.com
Purpose Thyroid hormones play an important role in the regulation of lipid and carbohydrate
metabolism, both of which are affected in patients with non-alcoholic steatohepatitis (NASH).
Anecdotally, we have observed that a number of patients with NASH carried a diagnosis of
hypothyroidism. However, it is unknown if thyroid dysfunction plays any role in the
pathogenesis of NASH. To further investigate this observation, we conducted a case-control
study to determine the association between hypothyroidism and NASH. Subjects and …