Nuclear receptors for thyroid hormone and steroids are members of a receptor superfamily
with similar molecular organization, but discrete transcriptional functions that define genomic
actions of these nonpeptide hormones. Nongenomic actions of thyroid hormone and
estrogens and androgens are initiated outside the nucleus, at receptors in the plasma
membrane or in cytoplasm; these actions are largely regarded to be unique to the respective
hormones. However, there is an increasing number of descriptions of overlapping …