Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice
MD Brandt, S Jessberger, B Steiner… - Molecular and Cellular …, 2003 - Elsevier
We here show that the early postmitotic stage of granule cell development during adult
hippocampal neurogenesis is characterized by the transient expression of calretinin (CR).
CR expression was detected as early as 1 day after labeling dividing cells with
bromodeoxyuridine (BrdU), but not before. Staining for Ki-67 confirmed that no CR-
expressing cells were in cell cycle. Early after BrdU, CR colocalized with immature neuronal
marker doublecortin; and later with persisting neuronal marker NeuN. BrdU/CR-labeled cells …
hippocampal neurogenesis is characterized by the transient expression of calretinin (CR).
CR expression was detected as early as 1 day after labeling dividing cells with
bromodeoxyuridine (BrdU), but not before. Staining for Ki-67 confirmed that no CR-
expressing cells were in cell cycle. Early after BrdU, CR colocalized with immature neuronal
marker doublecortin; and later with persisting neuronal marker NeuN. BrdU/CR-labeled cells …